• Generic Dermovate
  • Generic Dermovate
  • Generic Dermovate
  • Generic Dermovate
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Generic Dermovate


Generic Dermovate cream 0.05% belongs to a group of medicines called topical corticosteroids. Topical medicines are applied to the skin. Topical corticosteroids reduce redness, swelling, and irritation in certain skin conditions.

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Product name - Generic Dermovate cream 0.05% - Clostaf cream


Qualitative and quantitative composition - 1 g of Dermovate cream has clobetasol propionate - 0.5 mg (0.05% w/w); cetostearyl alcohol - 80 mg; propylene glycol - 475 mg; and chlorocresol - 0.75 mg. Other ingredients include sodium citrate, purified water, polyethylene glycol, glycerol stearate, glycerol monostearate, citric acid, and beeswax substitute.


Action mechanism - The active substance present is Clobetasol. It is a strong dose of topical corticosteroids. It is used to treat skin conditions that have not responded well to other corticosteroids. This may include severe cases of psoriasis and eczematous dermatitis. The medicine may be harmful to people for whom it has not been prescribed. The cream should be used for short-term therapy or relief of localized skin diseases only.


Indication - The Dermovate Cream is indicated to adults and children over 12 months old. It is only given when other corticosteroids failed to control the condition. The common indications are:

  • Psoriasis (psoriasis, thickened, inflamed and reddened skin) - often form silver/white-colored scales. Usually covering the affected area; except psoriasis with extensive plaques
  • Persistent eczema (non-infectious inflammatory skin disease)
  • Lichen planus - a skin condition that has itchy, reddish-purple, flattened nodules. It may occur at any place such as wrists, forearms or lower legs
  • Discoid lupus erythematosus - a skin disorder that affects the areas like the face, ears, and scalp. It causes scar formation on the skin as well as increased sensitivity to sunlight 


Mode of administration - It is a soft, white cream and applied topically. It is absorbed cutaneously. The cream is particularly suitable for damp surfaces.


Contraindication - Generic Dermovate - cream must not be used:

  • If you are allergic to clobetasol propionate or any of the other ingredients listed above
  • in rosacea - a red condition of facial skin
  • in acne vulgaris
  • in inflammatory skin disease affecting the face (especially around the mouth)
  • itching in the area of ​​the anus and genitals (perianal and genital pruritus)
  • in skin diseases caused by viruses (herpes simplex, chickenpox), bacteria, parasites or fungi
  • in certain skin diseases (skin tuberculosis, syphilitic skin involvement)
  • in skin rashes caused by vaccine reactions
  • in children under 12 years


Special cautions and warnings - Please talk to your doctor or pharmacist before using Dermovate cream. Take special care if you have an accompanying skin infection (by bacteria or fungi). You have to check for contraindications of Dermovate in those cases with the antibacterial or antifungal medicines. If you experience blurred vision or other vision problems, contact your doctor.

Its evidence of safety in use during pregnancy or lactation is not adequate in humans. Animal testing suggested abnormalities in the fetus. If you are pregnant or lactating or planning a baby consult your doctor before taking this medicine.

The use of Generic Dermovate cream is not expected to affect the ability to drive or operate machines. The cream contains chlorocresol, cetyl stearyl alcohol, and propylene glycol. Cetyl stearyl alcohol may cause localized skin irritation (e.g. contact dermatitis). Chlorocresol may produce an allergic reaction. Propylene glycol can cause skin irritation.

Interaction - No drug interactions reported to date


Side effects -  Generic Dermovate Side effects can affect your skin and other parts of your body when the medicine is absorbed through your skin and gets into the bloodstream. It produces systemic side effects.

Common side effects include:

  • Itchy skin
  • Local burning or pain in the affected skin area

Rare side effects include:

  • Stretch marks
  • Thinning of the skin (skin atrophy)
  • Visibility of the blood vessels below the surface of the skin (telangiectasia)

Very rare side effects include:

  • Acne
  • Changes in skin color
  • Dry skin
  • Hypersensitivity reaction (allergic reaction) at the site of administration
  • If you have psoriasis, nodules may develop with pus under the skin. These can rarely occur during or after treatment and are known as pustular psoriasis.
  • Increased body hair growth (hypertrichosis)
  • Irritation/pain at the site of administration
  • Rash or hives (urticaria)
  • Reddening
  • Skin infection
  • Thinning and wrinkling of the skin
  • Worsening of the complaints

Additional side effects in children include:

  • Delayed weight gain
  • Delayed growth

If you are having considerable side-effects, then stop using this medicine and contact your doctor immediately.


Interesting facts

  • Dermovate cream should not be applied to the face, eyelids, intertriginous areas (armpit and genital area)
  • Dermovate cream should not be used over a large skin area
  • Dermovate cream should not be used under the bandages or tight clothing or diapers
  • It should not be used in damaged skin surfaces (wounds, ulcers).
  • The chronic leg ulcers treatment is associated with a higher incidence of local hypersensitivity reactions and local infection risks
  • The face, forearms, and back of the hands are particularly prone to corticoid skin damage as they are exposed to sunlight. Application to these areas increases the side effects.
  • Use Generic Dermovate cream as sparingly as possible.
  • Use only when prescribed by your doctor
  • Use the medicine only as long as absolutely necessary to treat your skin condition.

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