Fliban Flibanserin


Fliban is a medicine containing Flibanserin, primarily used in females who have not experienced menopause but suffering from the loss of libido or Hypoactive Sexual Desire Disorder. The medicine is approved in the US to treat this disorder and increase sex drive in women. Poor libido creates trouble and mental distress to women suffering from it.

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Product name - Flibanserin, Fliban

Qualitative and quantitative composition - One tablet of Fliban has 100 mg of flibanserin. Other ingredients in the tablet with no medicinal function are croscarmellose sodium, hypromellose, lactose monohydrate, macrogol, magnesium stearate, microcrystalline cellulose, and talc. Iron oxide and titanium dioxide are also added as coloring agents.


Action mechanism - Flibanserin increases your sexual desire through an impact on brain neurotransmitter levels. Its function is different from the medication used to treat erectile dysfunction in men, where the flow of blood is improved in the genitals. However, it does tackle sexual dysfunction in women. The development of Flibanserin was made initially as an antidepressant was, but in 2015 FDA authorized it to be used as a therapy for loss of libido in women. The exact mode of action of this compound is still unknown, but a regular intake of the medicine increases norepinephrine and dopamine levels in your body while it reduces the serotonin level. Norepinephrine promotes sexual arousal and dopamine boosts the desire for sex.


Indication - Flibanserin is indicated to women with low sex drive or Hypoactive Sexual Desire Disorder in every situation or irrespective of other factors. This is not for women suffering from the lack of sex drive due to other reasons such as lack of time and energy, problems in relation, other medical conditions, or side effects of other medicines.


Mode of administration - It is available in a tablet form and should be taken regularly at bedtime for a period of 8 weeks. The action of the medicine has to be evaluated after 8 weeks and further action should be taken as per the guidance of your physician.


Contraindication - Flibanserin can interact with alcohol and increase your hypertension. This may result in unconsciousness and fainting. Flibanserin is processed by the liver and any form of liver disease can change the course of this processing. Therefore, it is not given to women with liver problems.

No studies have been carried out to confirm its safety to breastfeeding women. So it is advisable to refrain from having Flibanserin if you are a lactating woman. Flibanserin may or may not pass to your child during breastfeeding. Future studies will offer a better idea.


Special cautions and warnings - Never use Flibanserin tablets if you are having problems in the liver. If you are having any supplements then consult your doctor before taking Flibanserin.  This is a relatively new medicine. So the long term effect of this medicine is still not known and difficult to predict. It may have more side effects than medicinal benefits to many individuals. 


Drug interaction - Flibanserin can interact with different supplements and drugs and you should be cautious before taking Flibanserin. Common interactions include the following:

  • Cardiovascular medicines like verapamil and diltiazem

  • Different antibiotics, such as erythromycin and ciprofloxacin

  • Antifungal medicines, such as itraconazole and fluconazole

  • Medicines that are given to HIV patients including indinavir and ritonavir

  • Antidepressants like ionnefazodone

  • Different supplements

  • Medicines belong to CYP3A4 inhibitor group (A type of enzyme inhibitor)

It is also noted that Flibanserin can interact with grapefruit juice (a natural inhibitor of CYP3A4). So you should take grapefruit juice while taking this medicine.


Side effects - Side effects of Flibanserin not very pronounced and many women experience mind side effects. Some of the common side effects of flibanserin are

  • tiredness

  • remaining asleep

  • nausea

  • low blood pressure

  • loss of consciousness

  • dry mouth

  • dizziness

  • difficulty sleeping 

If you are having these side effects then consult your doctor on whether you continue the medication. If you are not experiencing any improvement even after 8 weeks of treatment then discontinue the medicine. 


Interesting facts

  • Never double the dose to compensate the missed dose

  • Initially, it was stated by the FDA to stop taking alcohol during the course of the medication as it may cause severe hypotension and fainting

  • In recent times, the FDA updated the alcohol guidance and now allowed the individual to take alcohol 2 hours prior to taking the medicine and only in the morning after taking the bedtime dose. If you are not sure about your drinking timing, avoid taking the medicine that day.

  • It is often called the female Viagra, although it has no similarity in the mode of action. It performs a role in women to help increase libido, while Viagra is to cure erectile dysfunction and has no role in affecting the male libido.

  • The tablets are pink in color to represent the female gender

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